Dosage & Administration
2 tablets twice a day
1 tablet twice a day

Apply 2 to 4 times a day on affected area

30 Tablets Blister / bottle
100 ml & 60 ml bottle

Each Arth-BRM tablet contains:
Ashwagandha (Withania somnifera) 100 mg
Triphala (T. chebula, T. Belerica,
E. Officinalis)
100 mg
Extracts (Ghanas) of
Saunth (Zingiber officinale) 50 mg
Sallaki (Boswellia serrata) 100 mg
Haldi (Curcuma longa) 100 mg
1. H. Ichikawa, Y. Takada, S. Shishodia, B. Jayaprakasam, M.G. Nair, B.B. Aggarwal. Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-kappaB (NF-kappaB) activation and NF-kappaB-regulated gene expression. Mol Cancer Ther, 5 (2006), pp. 1434–1445
2. V.H. Begum, J. Sadique. Long term effect of herbal drug Withania somnifera on adjuvant induced arthritis in rats. Indian J Exp Biol, 26 (1988), pp. 877–882
3. M. Rasool, P. Varalakshmi. Suppressive effect of Withania somnifera root powder on experimental gouty arthritis: an in vivo and in vitro study. Chem Biol Interact, 164 (2006), pp. 174–180.
4. Khanna D, Sethi G, Ahn KS, Pandey MK, Kunnumakkara AB, Sung B, Aggarwal A, Aggarwal BB. Natural products as a gold mine for arthritis treatment. Curr Opin Pharmacol. 2007 Jun;7(3):344-51.
5. Singh S, Aggarwal BB: Activation of transcription factor NFkappa B is suppressed by curcumin (diferuloylmethane). J Biol Chem 1995, 270:24995-25000.
6. Shishodia S, Amin HM, Lai R, Aggarwal BB: Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma. Biochem Pharmacol 2005, 70:700-713.
7. Kumar A, Dhawan S, Hardegen NJ, Aggarwal BB: Curcumin (diferuloylmethane) inhibition of tumor necrosis factor (TNF)- mediated adhesion of monocytes to endothelial cells bysuppression of cell surface expression of adhesion molecules and of nuclear factor-kappaB activation. Biochem Pharmacol 1998, 55:775-783.
8. Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB: Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation. Mol Pharmacol 2006, 69:195-206.
9. Skrzypczak-Jankun E, Zhou K, McCabe NP, Selman SH, Jankun J: Structure of curcumin in complex with lipoxygenase and its significance in cancer. Int J Mol Med 2003, 12:17-24.
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11. Onodera S, Kaneda K, Mizue Y, Koyama Y, Fujinaga M, Nishihira J: Macrophage migration inhibitory factor up-regulates expression of matrix metalloproteinases in synovial fibroblasts of rheumatoid arthritis. J Biol Chem 2000, 275:444-450.
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13. Jackson JK, Higo T, Hunter WL, Burt HM: The antioxidants curcumin and quercetin inhibit inflammatory processes associated with arthritis. Inflamm Res 2006, 55:168-175.
14. Lev-Ari S, Strier L, Kazanov D, Elkayam O, Lichtenberg D, Caspi D, Arber N: Curcumin synergistically potentiates the growth inhibitory and pro-apoptotic effects of celecoxib in osteoarthritis synovial adherent cells. Rheumatology (Oxford) 2006, 45:171-177.
15. Shakibaei M, John T, Schulze-Tanzil G, Lehmann I, Mobasheri A: Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis. Biochem Pharmacol 2007, in press.
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Explore Product
Arth - Brm - Liniment/Tablets
Therapeutic Category : Anti-arthritic Biological Response Modifier
Boswellic acids & oleoresin from Boswellia serrata, Ellagic acid, gallic acid, chebulinic acid, bellericanin, ß-sitosterol & flavanoids from Triphala, Phenolic gingerols from Zingiber officinale and Curcuminoids from Curcuma longa are the principle active / marker phytochemicals in Arth-BRM tablets. These multiple phytochemicals synergize to “switch-off” inflammatory & degenerative processes in musculoskeletal and synovial microenvironment by acting at numerous aspects of the inflammatory process.

Similarly, the botanicals and volatile oils in Arth-BRM liniment provide instant relief in musco-skeletal conditions due to local analgesic and counter-irritant effects.
  • Joint pain (Sandhishul)
  • Osteoarthropathy / Musculo-skeletal pain (Sandhigata vata)
  • Stiffness of joints (Sandhigraha)
  • Arthritis (Sandhi sotha)
  • Gout (Vatarakta)
  • Lumbago (Prsthna sula)