Directions for use :
Contents of one 3.8 gms sachet to be added to 200 ml (approximately one glassful) of freshly boiled and cooled water and used within 24 hours of reconstitution
Contents of one 19 gms sachet to be added to 1 litre of freshly boiled and cooled water and used within 24 hours of reconstitution.

1 to 5 glassful reconstituted with water, depending upon the severity of diarrhea and dehydration

3.8 gms & 19 gms sachets
Each 100 Gms Lomotral Oral Powder contains dried
aqueous extracts :
Kutaja (Holarrhena antidysenterica) 2.63 gms
Vidanga (Embelia ribes) 1.31 gms
Daruhalad (Berberis aristata) 1.31 gms
And Powders of
Samudra lavana (Sodium chloride) 18.95 gms
Bida lavana (Potassium chloride) 6.84 gms
Nimbu satva (Citric acid) 10.00 gms
Sharkara (Dextrose) Q.S
Explore Product
Lomotral - Oral Powder
Therapeutic Category : Anti-diarrhoeal + Oral Rehydration Salts
Lomotral controls diarrhoea with synergistic actions of botanicals Kutaja (Holarrhena antidysenterica), Vidanga (Embelia ribes) and Daruhalad (Berberis aristata) by:
  • Enhancing intestinal capillary micro-circulation to stimulate water absorption,
  • Reducing electrolyte secretion,
  • Mildly reducing gut motility,
  • Increase colonic water & electrolyte re-absorption and
  • Inactivating some of the diarrhoea inducing microbial toxins.
Lomotrol also replenishes vital electrolytes including sodium, potassium, citrates & glucose. The molar values of electrolytes in Lomotral are in keeping with the WHO / UNICEF defined criteria of acceptable molar range for electrolytes in ORS formulations.
In infants, children and adults :
  • Diarrhoeas of varied etiologies (Atisara, Balatisara)
  • Dysentery (Pravahika)
  • Dehydration (Nirjalana)
Studies & Trial Reports
1. Implementing the New Recommendations on the Clinical Management of Diarrhoea -Guidelines for Policy Makers and Programme Managers, World Health Organization, Document Production Services, Geneva, Switzerland, 2006.
2. Uttaratantrum. In Susruta Samhita: Kalpasthana- Uttartantra, III:370–409. Varanasi, India: Chowkhamba.
3. Cunha-Ferriera RM, Cash RA. History of the development of oral rehydration therapy. Clin Therap 1990; 12(Suppl A):2–13.
4. Bhishagratna K. An English Translation of the Sushruta Samhita. Varanasi, India: Chowkhamba Sanskrit Series Office, 1963, vol. 3, p. 352–356.
5. Radt, F., 1965. Elseviers encyclopaedia of organic chemistry, vol. 14.5. Springer-Verlag, New York, p. 4140s.
6. Pandey, G.S. (1979) In: K.C. Chunekar (Ed.), Bhauaprakash Nighantu (Indian Materia Medica of Sri Bravamisra 1500-1600. A.D.), 5th edn., Vidhyabhawan Ayurvedic Granthmala-28,Varanasi, pp. 347-348.
7. Sharma, P.V. (1978) Dravyaguna-Vijnana (vegetable drugs), Vol. II, 4th edn., Vidhyabhawan Ayurvedic Granthmala-3. Varanasi, pp. 463-466.
8. Singh, K.P. Clinical studies of Amoebiasis and Giardiasis evaluating the efficacy of Kutaja (Holarrhena autidysen terica) in Eutamoeta histotylica cyst passes. Ancient Science of Life1986; 5: 228-231.
9. Chopra, R.N., Chopra, I.C., Handa, K.L., Kapur, I.D., 1982. Chopras Indigenous drugs of India. Academic Press, New Delhi, India, p. 342.
10. Dutta NK, Iyer SN. Anti-amoebic value of berberine and kurchi alkaloids. J Indian Med Assoc. 1968; 50(8):349-52.
11. Aqil, F., Ahmad, I. Antibacterial properties of traditionally used Indian medicinal plants. Methods Find Exp Clin Pharmacol. 2007, 29(2): 79
12. Ballal M, Srujan D, Bhat K K, Shirwaikar A, Shivananda P G. Antibacterial activity of Holarrhena antidysenterica [kurchi] against the enteric Pathogens. Ind J Pharmac 2001; 32(6): 392-393
13. Kavitha D, Niranjali S. Inhibition of enteropathogenic Escherichia coli adhesion on host epithelial cells by Holarrhena antidysenterica (L.) WALL. Phytother Res. 2009; 23(9):1229-36.
14. Duita N K, Marker P H & Rao N R. Berberine in toxin induced experimental cholera. Br. J. Pharmacol. 1972; 44, 153 -159
15. Sabir M, Akhter M H & Bhide N K. Antagonism of cholera toxin by berberine in the gastrointestinal tract of adult rats. Indian J. Med. Res., 1977; 65, 305 -315.
16. Sack R B & Froehlich J L. Berberine inhibits intestinal secretory response of Vibrio cholerae and Escherichia coli enterotoxins. Infect. Immunol. 1982; 35, 471-475.
17. Swabb EA, Tai YH, Jordan L. Reversal of cholera toxin-induced secretion in rat ileum by luminal berberine. Am J Physiol 1981; 241:G248- G252.
18. Akhter MH, Sabir M, Bhide NK. Possible mechanism of antidiarrhoel effect of berberine. Indian J Med Res 1979; 70:233-241.
19. Yuan J, Shen XZ, Zhu XS. Effect of berberine on transit time of human small intestine. Chung Kuo Chung His I Chieh Ho Tsa Chih 1994.14:718-720.
20. Amin AH, Subbaiah TV, Abbasi KM. Berberine sulfate: antimicrobial activity, bioassay, and mode of action. Can J Microbiol 1969; 15:1067-1076.
21. Sun D, Abraham SN, Beachey EH. Influence of berberine sulfate on synthesis and expression of Pap fimbrial adhesin in uropathogenic Escherichia coli. Antimicrob Agents Chemother 1988;32:1274-1277.
22. Kaneda Y, Torii M, Tanaka T, Aikawa M. In vitro effects of berberine sulfate on the growth and structure of Entamoeba histolytica, Giardia lamblia, and Trichomonas vaginalis. Ann Trop Med Parasitol 1991; 85:417-425.
23. Ghosh AK, Bhattacharyya FK, Ghosh DK. Leismania donovani: amastigote inhibition and mode of action of berberine. Exp Parasitol 1985; 60:404-413.
24. Kaneda Y, Tanaka T, Saw T. Effects of berberine, a plant alkaloid, on the growth of anaerobic protozoa in axenic culture. Tokai J Exp Clin Med 1990; 15: 417-423.
25. Subbaiah TV, Amin AH. Effect of berberine sulphate on Entamoeba histolytica. Nature 1967; 215: 527-528.
26. Gufta 0 P, Anand K K, Mohd Ali M., Ray Ghatak B J, And Atal C K. In vitro anthelmintic activity of disalts of embelin. Indian J. Expt. Biol. 1976; 14, 356-357.
27. Guru L V, And Mishra D N. Anthelmintic activity of Embelia ribes (Burm) in vitro. Antiseptic 1964; 61, 545-550.
28. Guru L V and Mishra D N. Effect of alcoholic and aqueous extractives of Embelia ribes in the patients parasitized by ascarides. Indian Journal of Pharmacy. 1966b; 28, 3, 83.
29. Hördegen P, Cabaret J, Hertzberg H, Langhans W, Maurer V. In vitro screening of six anthelmintic plant products against larval Haemonchus contortus with a modified methylthiazolyl-tetrazolium reduction assay. J Ethnopharmacol. 2006; 108(1):85-9. Epub 2006 Apr27.
30. Hördegen P, Hertzberg H, Heilmann J, Langhans W, Maurer V The anthelmintic efficacy of five plant products against gastrointestinal trichostrongylids in artificially infected lambs. Journal of Ethnopharmacol 2006;108: 85–89.
31. Rani P and Khullar N. Antimicrobial Evaluation of some Medicinal Plants for their Antienteric Potential against Multi-drug Resistant Salmonella typhi. Phytother. Res. 2004; 18: 670–673